This year, the third culture thinkers in the Edge community have written 117 original essays (a document of 72,500 words) in response to the 2006 Edge Question — “What is your dangerous idea?”. Here you will find indications of a new natural philosophy, founded on the realization of the import of complexity, of evolution. Very complex systems — whether organisms, brains, the biosphere, or the universe itself — were not constructed by design; all have evolved. There is a new set of metaphors to describe ourselves, our minds, the universe, and all of the things we know in it.